Preoperative Anemia in Colon Cancer: Assessment of Risk Factors

Anemia is common in cancer patients and is associated with reduced survival. Re centime studies enumeration that treatment of anemia with blood transfusion in cancer patients is associated with increased infection risk, tumor recurrence, and mortality. We therefore investigated the incidence of preoperative anemia in colorectal cancer and assessed risk factors for anemia. future data were collected on 311 patients diagnosed with colorectal cancer over a 6-year period from 1994 through 1999. Patients were stratified by age, gender, presenting complaint, preoperative hematocrit, American Joint Committee on Cancer (AJCC) stage, and TNM classification. distinguishable variables were compared using Pearsons Chi-square analysis. Continuous variables were compared using Students t test. Differences were considered significant when P

CANCER, SECOND ONLY to heart disease, is a leading manage of death in the join States resulting in more than 500,000 deaths one-yearly. Cancers of the colon and rectum are estimated to be the third most common lick of cancer among both males and females and the second most common compositors case of cancer mortality in the United States. The average life sentence risk of developing colon cancer in the United States is now over 6 per cent.



Despite a autumn in the incidence of colorectal cancer since 1984 more than 135,000 untried cases affecting both men and women equally are diagnosed annually with more than 56,000 people ex pected to die on an annual basis.( n1) These statistics demonstrate the significant morbidity and mortality associated with colon cancer.

preoperative anemia is common in a variety of operative patients. Preoperative anemia has been documented in more than 34 per cent of noncardiac surgical veteran patients and in 32 per cent of surgical patients refusing blood transfusions for religious reasons.( n2, n3) In addition a retrospective study involving almost 2000 surgical patients documented that 28 per cent had preoperative hemoglobin...

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